• Association of use of the neonatal early-onset sepsis calculator with reduction in antibiotic therapy and safety: A systematic review and meta-analysis 

      Achten, Niek B.; Klingenberg, Claus; Benitz, William E.; Stocker, Martin; Schlapbach, Luregn J.; Giannoni, Eric; Bokelaar, Robin; Driessen, Gertjan J.A.; Brodin, Petter; Uthaya, Sabita; van Rossum, Annemarie M.C.; Plötz, Frans B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
      <i>Importance</i> - The neonatal early-onset sepsis (EOS) calculator is a clinical risk stratification tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on the effectiveness and safety of the EOS calculator is essential to inform clinicians considering implementation.<p> <p><i>Objective</i> - To assess the association between management of neonatal EOS ...
    • Stratification of Culture-Proven Early-Onset Sepsis Cases by the Neonatal Early-Onset Sepsis Calculator: An Individual Patient Data Meta-Analysis 

      Achten, Niek B.; Plötz, Frans B.; Klingenberg, Claus; Stocker, Martin; Bokelaar, Robin; Bijlsma, Merijn; Giannoni, Eric; van Rossum, Annemarie M.C.; Benitz, William E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-03)
      Objectives - To provide a comprehensive assessment of case stratification by the Neonatal Early-Onset Sepsis (EOS) Calculator, a novel tool for reducing unnecessary antibiotic treatment.<p> <p>Study design - A systematic review with individual patient data meta-analysis was conducted, extending PROSPERO record CRD42018116188. Cochrane, PubMed/MEDLINE, EMBASE, Web of Science, Google Scholar, and ...